Physical and Functional Interactions between ELL2 and RB in the Suppression of Prostate Cancer Cell Proliferation, Migration, and Invasion

Elongation factor, RNA polymerase II, 2 (ELL2) is expressed and regulated by androgens in the prostate. ELL2 and ELL-associated factor 2 (EAF2) form a stable complex, and their orthologs in Caenorhabditis elegans appear to be functionally similar. In C. elegans, the EAF2 ortholog eaf-1 was reported...

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Bibliographic Details
Main Authors: Xiaonan Qiu, Laura E. Pascal, Qiong Song, Yachen Zang, Junkui Ai, Katherine J. O’Malley, Joel B. Nelson, Zhou Wang
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558616301853