Tanshinone IIA attenuates polyethylene-induced osteolysis in a mouse model: The key role of miR-155-5p/FOXO3 axis
Osteolysis is a major complication of total joint arthroplasty, and tanshinone IIA (TAN) can attenuate the disorder. The current study aimed to verify the anti-osteolysis potential of TAN and explore the associated mechanism. Osteolysis was induced in mice and in human hFoB 1.19 osteoblasts using ul...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-12-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464621004333 |