Quinolone Resistance Reversion by Targeting the SOS Response

Suppression of the SOS response has been postulated as a therapeutic strategy for potentiating antimicrobial agents. We aimed to evaluate the impact of its suppression on reversing resistance using a model of isogenic strains of Escherichia coli representing multiple levels of quinolone resistance....

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Bibliographic Details
Main Authors: E. Recacha, J. Machuca, P. Díaz de Alba, M. Ramos-Guelfo, F. Docobo-Píérez, J. Rodriguez-Beltríéán, J. Blíéáázquez, A. Pascual, J. M. Rodríéááíguez-Martíéááíínez, Robert A. Bonomo
Format: Article
Language:English
Published: American Society for Microbiology 2017-10-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/5/e00971-17