Multi-target pharmacology: Possibilities and limitations of the skeleton key approach from a medicinal chemist perspective

Multi-target drugs have raised considerable interest in the last decade owing to their advantages in the treatment of complex diseases and health conditions linked to drug resistance issues. Prospective drug repositioning to treat comorbid conditions is an additional, overlooked application of multi...

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Bibliographic Details
Main Author: Alan eTalevi
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00205/full