Cross-species regulatory sequence activity prediction.

Machine learning algorithms trained to predict the regulatory activity of nucleic acid sequences have revealed principles of gene regulation and guided genetic variation analysis. While the human genome has been extensively annotated and studied, model organisms have been less explored. Model organi...

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Bibliographic Details
Main Author: David R Kelley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-07-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1008050