Clathrin- and dynamin-independent endocytosis of FGFR3--implications for signalling.

Endocytosis of tyrosine kinase receptors can influence both the duration and the specificity of the signal emitted. We have investigated the mechanisms of internalization of fibroblast growth factor receptor 3 (FGFR3) and compared it to that of FGFR1 which is internalized predominantly through clath...

Full description

Bibliographic Details
Main Authors: Ellen Margrethe Haugsten, Malgorzata Zakrzewska, Andreas Brech, Sascha Pust, Sjur Olsnes, Kirsten Sandvig, Jørgen Wesche
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3136467?pdf=render