MEN1/Menin regulates milk protein synthesis through mTOR signaling in mammary epithelial cells

Abstract The MEN1 gene, which encodes the protein Menin, was investigated for its regulatory role in milk protein synthesis in mammary glands. Menin responds to nutrient and hormone levels via the PI3K/Akt/mTOR pathway. Bovine mammary epithelial cells and tissues were used as experimental models in...

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Bibliographic Details
Main Authors: Honghui Li, Xue Liu, Zhonghua Wang, Xueyan Lin, Zhengui Yan, Qiaoqiao Cao, Meng Zhao, Kerong Shi
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06054-w