Beta-2 adrenergic receptors increase TREG cell suppression in an OVA-induced allergic asthma mouse model when mice are moderate aerobically exercised

Beta-2 adrenergic receptors increase TREG cell suppression in an OVA-induced allergic asthma mouse model when mice are moderate aerobically exercised

Abstract Background The potency of T regulatory (TREG) cells to inhibit T helper (Th)-driven immune cell responses has been linked to increased intracellular cyclic-AMP (cAMP) levels of TREG cells. In an ovalbumin (OVA)-driven allergic asthma mouse model, moderate aerobic exercise increases TREG cel...

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Bibliographic Details
Main Authors: Kari J. Dugger, Taylor Chrisman, Sarah L. Sayner, Parker Chastain, Kacie Watson, Robert Estes
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Immunology
Subjects:
Beta-2 adrenergic receptor
Exercise
TREG cell
cAMP
Online Access:http://link.springer.com/article/10.1186/s12865-018-0244-1

Internet

http://link.springer.com/article/10.1186/s12865-018-0244-1

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