Alanine Enhances Aminoglycosides-Induced ROS Production as Revealed by Proteomic Analysis

Alanine Enhances Aminoglycosides-Induced ROS Production as Revealed by Proteomic Analysis

Metabolite-enabled killing of antibiotic-resistant pathogens by antibiotics is an attractive strategy to manage antibiotic resistance. Our previous study demonstrated that alanine or/and glucose increased the killing efficacy of kanamycin on antibiotic-resistant bacteria, whose action is through up-...

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Bibliographic Details
Main Authors: Jin-zhou Ye, Yu-bin Su, Xiang-min Lin, Shi-shi Lai, Wan-xin Li, Farman Ali, Jun Zheng, Bo Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Microbiology
Subjects:
alanine
proteomics
metabolomics
reactive oxygen species
riboflavin metabolism
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00029/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2018.00029/full

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