Relative Stabilities of Conserved and Non-Conserved Structures in the OB-Fold Superfamily

Relative Stabilities of Conserved and Non-Conserved Structures in the OB-Fold Superfamily

The OB-fold is a diverse structure superfamily based on a β-barrel motif that is often supplemented with additional non-conserved secondary structures. Previous deletion mutagenesis and NMR hydrogen exchange studies of three OB-fold proteins showed that the structural stabilities of sites within the...

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Bibliographic Details
Main Authors: Andrei T. Alexandrescu, Sarah R. Sheftic, Kaitlyn M. Guardino, Robert E. Slattery
Format: Article
Language:English
Published: MDPI AG 2009-05-01
Series:International Journal of Molecular Sciences
Subjects:
protein folding
structural genomics
structure similarity
protein dynamics
modularity
Online Access:http://www.mdpi.com/1422-0067/10/5/2412/

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http://www.mdpi.com/1422-0067/10/5/2412/

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