N-Terminal Acetyltransferases Are Cancer-Essential Genes Prevalently Upregulated in Tumours

N-terminal acetylation (Nt-Ac) is an abundant eukaryotic protein modification, deposited in humans by one of seven N-terminal acetyltransferase (NAT) complexes composed of a catalytic and potentially auxiliary subunits. The involvement of NATs in cancers is being increasingly recognised, but a syste...

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Bibliographic Details
Main Authors: Costas Koufaris, Antonis Kirmizis
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/9/2631