Endogenous glucocorticoid increases the basal level of Treg-Th17 balance under early phase of stress

【Abstract】 Objective: To explore the changes of Treg-Th17 balance influenced by corticosterone, major ef-fect hormone of hypothalamic-pituitary-adrenal (HPA) axis under running stress. Methods: A total of 25 corticotropin-releasing hor-mone (CRH) wildtype (CRH+/+) and knockout (CRH-/-) mi...

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Bibliographic Details
Main Authors: WANG Hai-yan, GAO Wen-ting, HE Qing-hua, YANG Ce, GU Wei, YAN Jun, JIANG Jian-xin
Format: Article
Language:English
Published: Elsevier 2012-12-01
Series:Chinese Journal of Traumatology
Online Access:http://www.cjtrauma.com/apps/ojs/index.php/cjt/article/view/332