Identification and validation of Ifit1 as an important innate immune bottleneck.

The innate immune system plays important roles in a number of disparate processes. Foremost, innate immunity is a first responder to invasion by pathogens and triggers early defensive responses and recruits the adaptive immune system. The innate immune system also responds to endogenous damage signa...

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Bibliographic Details
Main Authors: Jason E McDermott, Keri B Vartanian, Hugh Mitchell, Susan L Stevens, Antonio Sanfilippo, Mary P Stenzel-Poore
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3380000?pdf=render