Maternal Microdeletion at the ICR in Mice Increases Offspring Susceptibility to Environmental Perturbation

Deficiency of methyl donor nutrients folate, choline, and methionine (methyl deficiency) during gestation can impair fetal development and perturb DNA methylation. Here, we assessed genetic susceptibility to methyl deficiency by comparing effects in wildtype C57BL/6J (B6) mice to mutant mice carryin...

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Bibliographic Details
Main Authors: Anandita Pal, Judy Oakes, Marwa Elnagheeb, Folami Y Ideraabdullah
Format: Article
Language:English
Published: SAGE Publishing 2020-11-01
Series:Epigenetics Insights
Online Access:https://doi.org/10.1177/2516865720970575