Maternal Microdeletion at the ICR in Mice Increases Offspring Susceptibility to Environmental Perturbation
Deficiency of methyl donor nutrients folate, choline, and methionine (methyl deficiency) during gestation can impair fetal development and perturb DNA methylation. Here, we assessed genetic susceptibility to methyl deficiency by comparing effects in wildtype C57BL/6J (B6) mice to mutant mice carryin...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2020-11-01
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Series: | Epigenetics Insights |
Online Access: | https://doi.org/10.1177/2516865720970575 |