Impaired Intracellular Trafficking Is a Common Disease Mechanism ofPMP22Point Mutations in Peripheral Neuropathies
The most common forms of hereditary motor and sensory neuropathies (HMSN) or Charcot–Marie–Tooth disease (CMT) are associated with mutations affecting myelin genes in the peripheral nervous system. A minor subgroup of CMT type 1A (CMT1A) is caused by point mutations in the gene encoding the peripher...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
1999-02-01
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| Series: | Neurobiology of Disease |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996198902273 |