Subtype- and antigenic site-specific differences in biophysical influences on evolution of influenza virus hemagglutinin

<p>Abstract</p> <p>Background</p> <p>Influenza virus undergoes rapid evolution by both antigenic shift and antigenic drift. Antibodies, particularly those binding near the receptor-binding site of hemagglutinin (HA) or the neuraminidase (NA) active site, are thought to...

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Bibliographic Details
Main Authors: Stray Stephen J, Pittman Lindsey B
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/9/1/91