Design, Synthesis and Evaluation of Branched RRWQWR-Based Peptides as Antibacterial Agents Against Clinically Relevant Gram-Positive and Gram-Negative Pathogens

Design, Synthesis and Evaluation of Branched RRWQWR-Based Peptides as Antibacterial Agents Against Clinically Relevant Gram-Positive and Gram-Negative Pathogens

Multidrug resistance of pathogenic bacteria has become a public health crisis that requires the urgent design of new antibacterial drugs such as antimicrobial peptides (AMPs). Seeking to obtain new, lactoferricin B (LfcinB)-based synthetic peptides as viable early-stage candidates for future develop...

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Bibliographic Details
Main Authors: Sandra C. Vega, Diana A. Martínez, María del S. Chalá, Hernán A. Vargas, Jaiver E. Rosas
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Microbiology
Subjects:
antibacterial activity
antimicrobial peptide
cationic peptide
lactoferrin
lactoferricin
multidrug resistance
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00329/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2018.00329/full

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