Epidermal growth factor mediates detachment from and invasion through collagen I and Matrigel in Capan-1 pancreatic cancer cells

<p>Abstract</p> <p>Background</p> <p>Pancreatic adenocarcinoma is a highly invasive neoplasm. Epidermal growth factor (EGF) and its receptor are over expressed in pancreatic cancer, and expression correlates with invasion and metastasis. We hypothesized that EGF recepto...

Full description

Bibliographic Details
Main Authors: Kuver Rahul, Shirk Andrew J
Format: Article
Language:English
Published: BMC 2005-03-01
Series:BMC Gastroenterology
Online Access:http://www.biomedcentral.com/1471-230X/5/12