Spatial modeling of the membrane-cytosolic interface in protein kinase signal transduction.

The spatial architecture of signaling pathways and the interaction with cell size and morphology are complex, but little understood. With the advances of single cell imaging and single cell biology, it becomes crucial to understand intracellular processes in time and space. Activation of cell surfac...

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Bibliographic Details
Main Authors: Wolfgang Giese, Gregor Milicic, Andreas Schröder, Edda Klipp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-04-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5908195?pdf=render