Universal human papillomavirus typing by whole genome sequencing following target enrichment: evaluation of assay reproducibility and limit of detection

Universal human papillomavirus typing by whole genome sequencing following target enrichment: evaluation of assay reproducibility and limit of detection

Abstract Background We recently described a method for unbiased detection of all known human papillomaviruses (HPV) types with the potential for the determination of their variant and integration from the resulting whole genome sequence data. Considering the complex workflow for target-enriched next...

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Bibliographic Details
Main Authors: Tengguo Li, Elizabeth R. Unger, Mangalathu S. Rajeevan
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Genomics
Subjects:
HPV typing
NGS
Target enrichment
Reproducibility
LOD
Online Access:http://link.springer.com/article/10.1186/s12864-019-5598-0

Internet

http://link.springer.com/article/10.1186/s12864-019-5598-0

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