Demethyleneberberine Protects against Hepatic Fibrosis in Mice by Modulating NF-κB Signaling

Demethyleneberberine Protects against Hepatic Fibrosis in Mice by Modulating NF-κB Signaling

Demethyleneberberine (DMB) is an essential metabolite of Berberine (BBR) in vivo. Recent reports have revealed multiple novel therapeutic applications of BBR. However, the pharmacological activities of DMB remain to be elucidated. This study aimed to demonstrate the hepatoprotective and anti-fibroti...

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Bibliographic Details
Main Authors: Yongchen Wang, Zheng Zhao, Yan Yan, Xiaoyan Qiang, Cuisong Zhou, Ruiyan Li, Huan Chen, Yubin Zhang
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:International Journal of Molecular Sciences
Subjects:
hepatic fibrosis
hepatic stellate cells
cell apoptosis
Demethyleneberberine
NF-κB
Online Access:http://www.mdpi.com/1422-0067/17/7/1036

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http://www.mdpi.com/1422-0067/17/7/1036

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