The role of STAT1 for crosstalk between fibroblasts and colon cancer cells

The role of STAT1 for crosstalk between fibroblasts and colon cancer cells

Signaling between tumor cells and the associated stroma has an important impact on cancer initiation and progression. The tumor microenvironment has a paradoxical role in tumor progression and fibroblasts, a major component of the tumor stroma, have been shown to either inhibit or promote cancer de...

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Bibliographic Details
Main Authors: Pawan eKaler, Benjamin Y Owusu, Leonard eAugenlicht, Lidija eKlampfer
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Oncology
Subjects:
Fibroblasts
Tumor Microenvironment
STAT1
Colon Cancer
proliferation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00088/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00088/full

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