Evaluation of hepatitis A vaccine in post-exposure prophylaxis, The Netherlands, 2004-2012.

BACKGROUND:The secondary attack rate of hepatitis A virus (HAV) among contacts of cases is up to 50%. Historically, contacts were offered immunoglobulin (IG, a human derived blood product) as post-exposure prophylaxis (PEP). Amid safety concerns about IG, HAV vaccine is increasingly recommended inst...

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Bibliographic Details
Main Authors: Jane Whelan, Gerard J Sonder, Lian Bovée, Arjen Speksnijder, Anneke van den Hoek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3798299?pdf=render