Interhelical H-Bonds Modulate the Activity of a Polytopic Transmembrane Kinase

Interhelical H-Bonds Modulate the Activity of a Polytopic Transmembrane Kinase

DesK is a Histidine Kinase that allows <i>Bacillus subtilis</i> to maintain lipid homeostasis in response to changes in the environment. It is located in the membrane, and has five transmembrane helices and a cytoplasmic catalytic domain. The transmembrane region triggers the phosphoryla...

Full description

Bibliographic Details
Main Authors: Juan Cruz Almada, Ana Bortolotti, Jean Marie Ruysschaert, Diego de Mendoza, María Eugenia Inda, Larisa Estefanía Cybulski
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biomolecules
Subjects:
transmembrane protein interactions
hydrogen bond interaction
signal transduction
histidine kinase
dimerisation motif
receptor
Online Access:https://www.mdpi.com/2218-273X/11/7/938

Internet

https://www.mdpi.com/2218-273X/11/7/938

Similar Items