Blowing epithelial cell bubbles with GumB: ShlA-family pore-forming toxins induce blebbing and rapid cellular death in corneal epithelial cells.

Blowing epithelial cell bubbles with GumB: ShlA-family pore-forming toxins induce blebbing and rapid cellular death in corneal epithelial cells.

Medical devices, such as contact lenses, bring bacteria in direct contact with human cells. Consequences of these host-pathogen interactions include the alteration of mammalian cell surface architecture and induction of cellular death that renders tissues more susceptible to infection. Gram-negative...

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Bibliographic Details
Main Authors: Kimberly M Brothers, Jake D Callaghan, Nicholas A Stella, Julianna M Bachinsky, Mohammed AlHigaylan, Kara L Lehner, Jonathan M Franks, Kira L Lathrop, Elliot Collins, Deanna M Schmitt, Joseph Horzempa, Robert M Q Shanks
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007825

Internet

https://doi.org/10.1371/journal.ppat.1007825

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