Tumors exploit CXCR4hiCD62Llo aged neutrophils to facilitate metastatic spread

Tumors exploit CXCR4hiCD62Llo aged neutrophils to facilitate metastatic spread

Granulocytes are key players in cancer metastasis. While tumor-induced de novo expansion of immunosuppressive myeloid-derived suppressor cells (MDSCs) is well-described, the fate and contribution of terminally differentiated mature neutrophils to the metastatic process remain poorly understood. Here...

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Bibliographic Details
Main Authors: Zhenzi Peng, Cuiwei Liu, Aaron R. Victor, Duo-Yao Cao, Luciana C. Veiras, Ellen A. Bernstein, Zakir Khan, Jorge F. Giani, Xiaojiang Cui, Kenneth E. Bernstein, Derick Okwan-Duodu
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:OncoImmunology
Subjects:
metastasis
aged neutrophils
neutrophil homeostasis
inflammation
Online Access:http://dx.doi.org/10.1080/2162402X.2020.1870811

Internet

http://dx.doi.org/10.1080/2162402X.2020.1870811

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