Yin-Yang Mechanisms Regulating Lipid Peroxidation of Docosahexaenoic Acid and Arachidonic Acid in the Central Nervous System

Yin-Yang Mechanisms Regulating Lipid Peroxidation of Docosahexaenoic Acid and Arachidonic Acid in the Central Nervous System

Phospholipids in the central nervous system (CNS) are rich in polyunsaturated fatty acids (PUFAs), particularly arachidonic acid (ARA) and docosahexaenoic acid (DHA). Besides providing physical properties to cell membranes, these PUFAs are metabolically active and undergo turnover through the “deacy...

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Bibliographic Details
Main Authors: Bo Yang, Kevin L. Fritsche, David Q. Beversdorf, Zezong Gu, James C. Lee, William R. Folk, C. Michael Greenlief, Grace Y. Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Neurology
Subjects:
arachidonic acid
docosahexaenoic acid
cPLA2
iPLA2
lipid peroxidation
4-hydroxyhexenal
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00642/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2019.00642/full

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