Ceramides and sphingomyelinases in senile plaques

Ceramides and sphingomyelinases in senile plaques

The senile plaque is a hallmark lesion of Alzheimer disease (AD). We compared, without a priori, the lipidome of the senile plaques and of the adjacent plaque-free neuropil. The analysis by liquid chromatography coupled with electrospray ionization mass spectrometry revealed that laser microdissecte...

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Bibliographic Details
Main Authors: Maï Panchal, Mathieu Gaudin, Adina N. Lazar, Elisa Salvati, Isabelle Rivals, Sophie Ayciriex, Luce Dauphinot, Delphine Dargère, Nicolas Auzeil, Massimo Masserini, Olivier Laprévote, Charles Duyckaerts
Format: Article
Language:English
Published: Elsevier 2014-05-01
Series:Neurobiology of Disease
Subjects:
Alzheimer disease
Senile plaques
Laser microdissection
Lipidomics
Mass spectrometry
Ceramides
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114000242

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http://www.sciencedirect.com/science/article/pii/S0969996114000242

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