Oncogenic seRNA functional activation: a novel mechanism of tumorigenesis
Abstract seRNA is a noncoding RNA (ncRNA) transcribed from active super-enhancer (SE), through which SE exerts biological functions and participates in various physiological and pathological processes. seRNA recruits cofactor, RNA polymerase II and mediator to constitute and stabilize chromatin loop...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-04-01
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Series: | Molecular Cancer |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12943-020-01195-5 |