Biochemical Signals Mediate the Crosstalk between Cartilage and Bone in Osteoarthritis

Osteochondral junction is a functional unit comprising the articular cartilage, calcified cartilage, and subchondral bone. Alteration in any component of this composite unit can disrupt the joint integrity and function directly or indirectly. Biochemical signals mediate the crosstalk between tissues...

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Bibliographic Details
Main Authors: Xuchang Zhou, Hong Cao, Yu Yuan, Wei Wu
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2020/5720360