Pathological characterization of T2*-weighted MRI contrast in the striatum of Huntington’s disease patients

Pathological characterization of T2*-weighted MRI contrast in the striatum of Huntington’s disease patients

Previous MRI studies consistently reported iron accumulation within the striatum of patients with Huntington’s disease (HD). However, the pattern and origin of iron accumulation is poorly understood. This study aimed to characterize the histopathological correlates of iron-sensitive ex vivo MRI cont...

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Bibliographic Details
Main Authors: Marjolein Bulk, Ingrid Hegeman-Kleinn, Boyd Kenkhuis, Ernst Suidgeest, Willeke van Roon-Mom, Jan Lewerenz, Sjoerd van Duinen, Itamar Ronen, Louise van der Weerd
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:NeuroImage: Clinical
Subjects:
MRI
Iron
Huntington’s disease
Microglia
Astrocytes
Striatum
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158220303351

Internet

http://www.sciencedirect.com/science/article/pii/S2213158220303351

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