CCNDBP1, a Prognostic Marker Regulated by DNA Methylation, Inhibits Aggressive Behavior in Dedifferentiated Liposarcoma via Repressing Epithelial Mesenchymal Transition

CCNDBP1, a Prognostic Marker Regulated by DNA Methylation, Inhibits Aggressive Behavior in Dedifferentiated Liposarcoma via Repressing Epithelial Mesenchymal Transition

The present study aimed to explore the prognostic value, function, and mechanism of CCNDBP1 in dedifferentiated liposarcoma (DDL). Immunohistochemistry staining was used to analyze the protein expression of CCNDBP1 in tissue specimens. After silencing CCNDBP1 in LPS853 and overexpressing CCNDBP1 in...

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Bibliographic Details
Main Authors: Lingge Yang, Zhiqiang Wu, Wei Sun, Peng Luo, Shiqi Chen, Yong Chen, Wangjun Yan, Yan Li, Chunmeng Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
dedifferentiated liposarcoma
CCNDBP1
prognosis prediction
invasion and metastasis
epithelial-mesenchymal transition
DNA methylation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.687012/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.687012/full

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