The Delta-Subunit Selective GABAA Receptor Modulator, DS2, Improves Stroke Recovery via an Anti-inflammatory Mechanism

The Delta-Subunit Selective GABAA Receptor Modulator, DS2, Improves Stroke Recovery via an Anti-inflammatory Mechanism

Inflammatory processes are known to contribute to tissue damage in the central nervous system (CNS) across a broad range of neurological conditions, including stroke. Gamma amino butyric acid (GABA), the main inhibitory neurotransmitter in the CNS, has been implicated in modulating peripheral immune...

Full description

Bibliographic Details
Main Authors: Silke Neumann, Lily Boothman-Burrell, Emma K. Gowing, Thomas A. Jacobsen, Philip K. Ahring, Sarah L. Young, Karin Sandager-Nielsen, Andrew N. Clarkson
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Neuroscience
Subjects:
stroke
inflammation
GABA
immune response
neuroinflammation
functional recovery
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01133/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.01133/full

Similar Items