Acute treatment with docosahexaenoic acid complexed to albumin reduces injury after a permanent focal cerebral ischemia in rats.

Acute treatment with docosahexaenoic acid complexed to albumin reduces injury after a permanent focal cerebral ischemia in rats.

Docosahexaenoic acid complexed to albumin (DHA-Alb) is highly neuroprotective after temporary middle cerebral artery occlusion (MCAo), but whether a similar effect occurs in permanent MCAo is unknown. Male Sprague-Dawley rats (270-330 g) underwent permanent MCAo. Neurological function was evaluated...

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Bibliographic Details
Main Authors: Tiffany N Eady, Larissa Khoutorova, Daniela V Anzola, Sung-Ha Hong, Andre Obenaus, Alena Mohd-Yusof, Nicolas G Bazan, Ludmila Belayev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3806755?pdf=render

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http://europepmc.org/articles/PMC3806755?pdf=render

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