The p66(Shc) adaptor protein controls oxidative stress response in early bovine embryos.

The in vitro production of mammalian embryos suffers from high frequencies of developmental failure due to excessive levels of permanent embryo arrest and apoptosis caused by oxidative stress. The p66Shc stress adaptor protein controls oxidative stress response of somatic cells by regulating intrace...

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Bibliographic Details
Main Authors: Dean H Betts, Nathan T Bain, Pavneesh Madan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3901717?pdf=render