The tyrosine kinase inhibitor dasatinib induces a marked adipogenic differentiation of human multipotent mesenchymal stromal cells.

<h4>Background</h4>The introduction of specific BCR-ABL inhibitors in chronic myelogenous leukemia therapy has entirely mutated the prognosis of this hematologic cancer from being a fatal disorder to becoming a chronic disease. Due to the probable long lasting treatment with tyrosine-kin...

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Bibliographic Details
Main Authors: Adriana Borriello, Ilaria Caldarelli, Maria Assunta Basile, Debora Bencivenga, Annunziata Tramontano, Silverio Perrotta, Fulvio Della Ragione, Adriana Oliva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22164306/pdf/?tool=EBI