Bortezomib-induced hyponatremia: tolvaptan therapy permits continuation of lenalidomide, bortezomib and dexamethasone therapy in relapsed myeloma

Abstract The development of hyponatremia due to syndrome of inappropriate antidiuretic hormone secretion (SIADH) is well recognised in multiple myeloma (MM). SIADH, due to either MM or Bortezomib can be hazardous as severe hyponatremia may develop if large volumes of hypotonic intravenous fluid are...

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Bibliographic Details
Main Authors: N. O’Connor-Byrne, S. Glavey, R. Tudor, P. Murphy, C. J. Thompson, J. Quinn
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Experimental Hematology & Oncology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40164-019-0128-y