Locus Coeruleus to Paraventricular Thalamus Projections Facilitate Emergence From Isoflurane Anesthesia in Mice

Locus Coeruleus to Paraventricular Thalamus Projections Facilitate Emergence From Isoflurane Anesthesia in Mice

Locus coeruleus (LC) sends widespread outputs to many brain regions to modulate diverse functions, including sleep/wake states, attention, and the general anesthetic state. The paraventricular thalamus (PVT) is a critical thalamic area for arousal and receives dense tyrosine-hydroxylase (TH) inputs...

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Bibliographic Details
Main Authors: Yawen Ao, Bo Yang, Caiju Zhang, Bo Wu, Xuefen Zhang, Dong Xing, Haibo Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
locus coeruleus
paraventricular thalamus
general anesthesia
emergence
optogenetics and DREADDs
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.643172/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.643172/full

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