Norovirus Changes Susceptibility to Type 1 Diabetes by Altering Intestinal Microbiota and Immune Cell Functions

Norovirus Changes Susceptibility to Type 1 Diabetes by Altering Intestinal Microbiota and Immune Cell Functions

Environmental factors contribute to Type 1 diabetes (T1D) susceptibility. The gut microbiome, which includes bacteria, viruses, and fungi, contributes to this environmental influence, and can induce immunological changes. The gut viral component of the microbiome, related to T1D has mostly focused o...

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Bibliographic Details
Main Authors: James A. Pearson, Ningwen Tai, Dilrukshi K. Ekanayake-Alper, Jian Peng, Youjia Hu, Karl Hager, Susan Compton, F. Susan Wong, Peter C. Smith, Li Wen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
norovirus
type 1 diabetes
non-obese diabetic mice
gut microbiota
Tuft cells
Treg
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02654/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02654/full

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