Chitosan Glutamate-Coated Niosomes: A Proposal for Nose-to-Brain Delivery

Chitosan Glutamate-Coated Niosomes: A Proposal for Nose-to-Brain Delivery

The aim of this in vitro study is to prepare and characterize drug free and pentamidine loaded chitosan glutamate coated niosomes for intranasal drug delivery to reach the brain through intranasal delivery. Mucoadhesive properties and stability testing in various environments were evaluated to exami...

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Bibliographic Details
Main Authors: Federica Rinaldi, Patrizia N. Hanieh, Lik King Nicholas Chan, Livia Angeloni, Daniele Passeri, Marco Rossi, Julie Tzu-Wen Wang, Anna Imbriano, Maria Carafa, Carlotta Marianecci
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Pharmaceutics
Subjects:
nose to brain delivery
central nervous system (CNS)
chitosan glutamate
niosomes
mucin
pentamidine
dynamic light scattering (DLS)
atomic force microscopy (AFM)
Online Access:http://www.mdpi.com/1999-4923/10/2/38

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http://www.mdpi.com/1999-4923/10/2/38

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