125I Seed Promotes Apoptosis in Non-small Lung Cancer Cells via the p38 MAPK-MDM2-p53 Signaling Pathway

Purpose:125I seeds were effective in the treatment of non-small cell lung cancer in previous research. However, the exact signaling pathway-mediated apoptosis mechanism is still unclear. The present study analyzed the effects and potential mechanisms of 125I seed on the growth and migration of A549...

Full description

Bibliographic Details
Main Authors: Tao Zhang, ZhiQiang Mo, Guangfeng Duan, Rijie Tang, Fujun Zhang, Mingjian Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
p38
p53
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.582511/full