Alterations in cerebellar physiology are associated with a stiff-legged gait in Atcayji-hes mice

Alterations in cerebellar physiology are associated with a stiff-legged gait in Atcayji-hes mice

Recent evidence suggests that dystonia, a movement disorder characterized by sustained involuntary muscle contractions, can be associated with cerebellar abnormalities. The basis for how functional changes in the cerebellum can cause dystonia is poorly understood. Here we identify alterations in phy...

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Bibliographic Details
Main Authors: Katiuska Luna-Cancalon, Kristine M. Sikora, Samuel S. Pappas, Vikrant Singh, Heike Wulff, Henry L. Paulson, Margit Burmeister, Vikram G. Shakkottai
Format: Article
Language:English
Published: Elsevier 2014-07-01
Series:Neurobiology of Disease
Subjects:
Dystonia
Ataxia
Cerebellum
Purkinje cells
Deep cerebellar nuclei
Patch-clamp
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114000813

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http://www.sciencedirect.com/science/article/pii/S0969996114000813

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