Pathogenesis of SCA3 and implications for other polyglutamine diseases

by Hayley S. McLoughlin, Lauren R. Moore, Henry L. Paulson
Published 2020-02-01

Splice isoform-specific suppression of the CaV2.1 variant underlying spinocerebellar ataxia type 6

by Wei-Ling Tsou, Bing-Wen Soong, Henry L. Paulson, Edgardo Rodríguez-Lebrón
Published 2011-09-01

Splice isoforms of the polyglutamine disease protein ataxin-3 exhibit similar enzymatic yet different aggregation properties.

by Ginny Marie Harris, Katerina Dodelzon, Lijie Gong, Pedro Gonzalez-Alegre, Henry L Paulson
Published 2010-10-01

Corrigendum to “In vivo suppression of polyglutamine neurotoxicity by C-terminus of Hsp70-interacting protein (CHIP) supports an aggregation model of pathogenesis”[Neurobiology of...

by Aislinn J. Williams, Tina M. Knutson, Veronica F. Colomer Gould, Henry L. Paulson
Published 2012-05-01

In vivo suppression of polyglutamine neurotoxicity by C-terminus of Hsp70-interacting protein (CHIP) supports an aggregation model of pathogenesis

by Aislinn J. Williams, Tina M. Knutson, Veronica F. Colomer Gould, Henry L. Paulson
Published 2009-03-01

Valosin-containing protein (VCP/p97) is an activator of wild-type ataxin-3.

by Mário N Laço, Luisa Cortes, Sue M Travis, Henry L Paulson, A Cristina Rego
Published 2012-01-01

Loss of the Spinocerebellar Ataxia type 3 disease protein ATXN3 alters transcription of multiple signal transduction pathways.

by Li Zeng, Dapeng Zhang, Hayley S McLoughlin, Annie J Zalon, L Aravind, Henry L Paulson
Published 2018-01-01

Fbxo2 mediates clearance of damaged lysosomes and modifies neurodegeneration in the Niemann-Pick C brain

by Elaine A. Liu, Mark L. Schultz, Chisaki Mochida, Chan Chung, Henry L. Paulson, Andrew P. Lieberman
Published 2020-10-01

Transcriptional changes and developmental abnormalities in a zebrafish model of myotonic dystrophy type 1

by Peter K. Todd, Feras Y. Ackall, Junguk Hur, Kush Sharma, Henry L. Paulson, James J. Dowling
Published 2014-01-01

Understanding the role of the Josephin domain in the PolyUb binding and cleavage properties of ataxin-3.

by Giuseppe Nicastro, Sokol V Todi, Ezgi Karaca, Alexandre M J J Bonvin, Henry L Paulson, Annalisa Pastore
Published 2010-08-01

Differential toxicity of ataxin-3 isoforms in Drosophila models of Spinocerebellar Ataxia Type 3

by Sean L. Johnson, Jessica R. Blount, Kozeta Libohova, Bedri Ranxhi, Henry L. Paulson, Wei-Ling Tsou, Sokol V. Todi
Published 2019-12-01

Alterations in cerebellar physiology are associated with a stiff-legged gait in Atcayji-hes mice

by Katiuska Luna-Cancalon, Kristine M. Sikora, Samuel S. Pappas, Vikrant Singh, Heike Wulff, Henry L. Paulson, Margit Burmeister, Vikram G. Shakkottai
Published 2014-07-01

Establishment of a novel fluorescence-based method to evaluate chaperone-mediated autophagy in a single neuron.

by Takahiro Seki, Ken-ich Yoshino, Shigeru Tanaka, Eisuke Dohi, Tomoya Onji, Kazuhiro Yamamoto, Izumi Hide, Henry L Paulson, Naoaki Saito, Norio Sakai
Published 2012-01-01

Characterization of an Expanded Glutamine Repeat Androgen Receptor in a Neuronal Cell Culture System

by Brian P. Brooks, Henry L. Paulson, Diane E. Merry, Edgar F. Salazar-Grueso, Albert O. Brinkmann, Elizabeth M. Wilson, Kenneth H. Fischbeck
Published 1997-01-01

Distinct C9orf72-Associated Dipeptide Repeat Structures Correlate with Neuronal Toxicity.

by Brittany N Flores, Mark E Dulchavsky, Amy Krans, Michael R Sawaya, Henry L Paulson, Peter K Todd, Sami J Barmada, Magdalena I Ivanova
Published 2016-01-01

The ubiquitin conjugating enzyme Ube2W regulates solubility of the Huntington's disease protein, huntingtin

by Bo Wang, Li Zeng, Sean A. Merillat, Svetlana Fischer, Joseph Ochaba, Leslie M. Thompson, Sami J. Barmada, Kenneth M. Scaglione, Henry L. Paulson
Published 2018-01-01

Histone deacetylases suppress CGG repeat-induced neurodegeneration via transcriptional silencing in models of fragile X tremor ataxia syndrome.

by Peter K Todd, Seok Yoon Oh, Amy Krans, Udai B Pandey, Nicholas A Di Prospero, Kyung-Tai Min, J Paul Taylor, Henry L Paulson
Published 2010-12-01

Ataxin-3 plays a role in mouse myogenic differentiation through regulation of integrin subunit levels.

by Maria do Carmo Costa, Fernanda Bajanca, Ana-João Rodrigues, Ricardo J Tomé, Garry Corthals, Sandra Macedo-Ribeiro, Henry L Paulson, Elsa Logarinho, Patrícia Maciel
Published 2010-07-01

Evaluation of Antisense Oligonucleotides Targeting ATXN3 in SCA3 Mouse Models

by Lauren R. Moore, Gautam Rajpal, Ian T. Dillingham, Maya Qutob, Kate G. Blumenstein, Danielle Gattis, Gene Hung, Holly B. Kordasiewicz, Henry L. Paulson, Hayley S. McLoughlin
Published 2017-06-01

Protocol for an observational cohort study identifying factors predicting accurately end of life in dementia with Lewy bodies and promoting quality end-of-life experiences: the PAC...

by Melissa J Armstrong, Henry L Paulson, Susan M Maixner, Julie A Fields, Angela M Lunde, Bradley F Boeve, Carol Manning, James E Galvin, Angela S Taylor
Published 2021-06-01