Emerging understanding of multiscale tumor heterogeneity

Emerging understanding of multiscale tumor heterogeneity

Cancer is a multifaceted disease characterized by heterogeneous genetic alterations and cellular metabolism, at the organ, tissue, and cellular level. Key features of cancer heterogeneity are summarized by ten acquired capabilities, which govern malignant transformation and progression of invasive t...

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Bibliographic Details
Main Authors: Michael J Gerdes, Anup eSood, Christopher eSevinsky, Andrew ePris, Maria Ildiko Zavodszky, Fiona eGinty
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Oncology
Subjects:
Tumor Microenvironment
Cancer
Next-generation sequencing
heterogeneity
multiplexing
tumor mechanisms
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00366/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00366/full

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