Epigenetic modifications by polyphenolic compounds alter gene expression in the hippocampus

In this study, we developed an experimental protocol leveraging enhanced reduced representation bisulphite sequencing to investigate methylation and gene expression patterns in the hippocampus in response to polyphenolic compounds. We report that the administration of a standardized bioavailable pol...

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Bibliographic Details
Main Authors: Tal Frolinger, Francis Herman, Ali Sharma, Steven Sims, Jun Wang, Giulio Maria Pasinetti
Format: Article
Language:English
Published: The Company of Biologists 2018-10-01
Series:Biology Open
Subjects:
DMR
Online Access:http://bio.biologists.org/content/7/10/bio035196