In silico Designed Ebola Virus T-Cell Multi-Epitope DNA Vaccine Constructions Are Immunogenic in Mice

In silico Designed Ebola Virus T-Cell Multi-Epitope DNA Vaccine Constructions Are Immunogenic in Mice

<i>Background</i>: The lack of effective vaccines against Ebola virus initiates a search for new approaches to overcoming this problem. The aim of the study was to design artificial polyepitope T-cell immunogens&#8212;candidate DNA vaccines against Ebola virus and to evaluate their c...

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Bibliographic Details
Main Authors: Sergei I. Bazhan, Denis V. Antonets, Larisa I. Karpenko, Svetlana F. Oreshkova, Olga N. Kaplina, Ekaterina V. Starostina, Sergei G. Dudko, Sofia A. Fedotova, Alexander A. Ilyichev
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Vaccines
Subjects:
ebola virus disease
artificial T-cell antigens
DNA vaccine constructs
computer design
gene expression
immunogenicity
Online Access:https://www.mdpi.com/2076-393X/7/2/34

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https://www.mdpi.com/2076-393X/7/2/34

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