Effect of Sialic Acid on Mammalian Cell Culture and Protein Expression: A Potential Productivity Enhancer for Biopharmaceutical Cell Culture Processes

Improved productivity of the two most commonly used cell lines in the biopharmaceutical industry, such as human embryonic kidney 293 (HEK293) and Chinese hamster ovary (CHO), could reduce production costs and increase manufacturing capacity. One method for increasing protein productivity is the addi...

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Bibliographic Details
Main Authors: Xiangsong Chen, Shang Xiao, Jinyong Wu, Jianming Yao
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Processes
Subjects:
CHO
ROS
Online Access:https://www.mdpi.com/2227-9717/8/11/1449