Transition-metal-free formal cross-coupling of aryl methyl sulfoxides and alcohols via nucleophilic activation of C-S bond

Cross-coupling processes without the use of transition metals are challenging to achieve. Here, the authors show a transition-metal-free cross-coupling utilizing aryl(heteroaryl) methyl sulfoxides and alcohols to afford alkyl aryl(heteroaryl) ethers and propose a nucleophilic addition mechanism base...

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Bibliographic Details
Main Authors: Guolin Li, Yexenia Nieves-Quinones, Hui Zhang, Qingjin Liang, Shuaisong Su, Qingchao Liu, Marisa C. Kozlowski, Tiezheng Jia
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16713-8