Polysaccharide from Lentinus edodes inhibits the immunosuppressive function of myeloid-derived suppressor cells.

Reversing the function of immune suppressor cells may improve the efficacy of cancer therapy. Here, we have isolated a novel polysaccharide MPSSS (577.2 Kd) from Lentinus edodes and examined its effects on differentiation and function of myeloid-derived suppressor cells (MDSCs). MPSSS is composed of...

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Bibliographic Details
Main Authors: Hao Wu, Ning Tao, Xiaoman Liu, Xiao Li, Jian Tang, Chungwah Ma, Xiaofei Xu, Haitao Shao, Baidong Hou, Hui Wang, Zhihai Qin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3525656?pdf=render