A Novel Biomarker Panel Examining Response to Gemcitabine with or without Erlotinib for Pancreatic Cancer Therapy in NCIC Clinical Trials Group PA.3.

PURPOSE:NCIC Clinical Trials Group PA.3 was a randomized control trial that demonstrated improved overall survival (OS) in patients receiving erlotinib in addition to gemcitabine for locally advanced or metastatic pancreatic cancer. Prior to therapy, patients had plasma samples drawn for future stud...

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Bibliographic Details
Main Authors: David B Shultz, Jonathan Pai, Wayland Chiu, Kendall Ng, Madeline G Hellendag, Gregory Heestand, Daniel T Chang, Dongsheng Tu, Malcolm J Moore, Wendy R Parulekar, Albert C Koong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4725948?pdf=render